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Severe hyperthermia and seizures, sometimes fatal, have been reported in association with the combined use of tricyclic antidepressants and MAOIs. buy effexor doctor prescription Geriatric Use Of the 2,897 patients in Phase and Phase depression studies with Effexor, 12 357 were 65 years of age or over. Food did not affect the bioavailability of venlafaxine or its active metabolite, ODV. This medication may rarely cause very serious condition called serotonin syndrome. This finding was confirmed in vivo by clinical drug interaction study in which venlafaxine did not inhibit the metabolism of caffeine, CYP1A2 substrate.

 
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