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Hypertensive Patients with Left Ventricular Hypertrophy In the LIFE study, adverse events with COZAAR were similar to those reported previously for patients with hypertension. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Losartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Conversion of losartan to losartan kaufen on-line its active metabolite after intravenous administration is not affected by ketoconazole, an inhibitor of P450 3A4. Scientists believe that common hypertension drug called losartan could have saved him. By blocking the action of angiotensin, losartan dilates blood vessels and thereby reduces blood pressure. Merck is providing information on 2009 and 2008 non-GAAP earnings per share that excludes certain items because of the nature of these items and the impact they have on the analysis of underlying business performance and trends.